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Research Updates

Articles from around the world on new research updates for bipolar disorder

November 2016

Sex differences in gray matter reductions may underlie risk of substance abuse in adolescents with bipolar disorder (United States) 

Achieving equality in mental health for all (Global)

Scientists identify commonly affected genes sets among people with three mental disorders (United States)    

Study examines effects of internet-based cognitive behavior therapy for social anxiety (China)

Gut microbes can modify our mood and behaviour, research reveals (Spain)                                             

A lab test for Bipolar Disorder? (United States)                                                                        

October 2016

Study finds strong link between childhood adversity and bipolar disorder diagnosis (United Kingdom)            

Scientists identify new pathway in the brain that can be targeted to alleviate depression (United States)           

Researchers find common brain abnormalities shared across multiple emotional disorders (United States)     

Memory performance predicts recurrence of mania in bipolar disorder following psychotherapy: A preliminary study (United States and Germany)

Search for plasma biomarkers in drug-free patients with bipolar disorder and schizophrenia using metabolome analysis  (Japan)

Independent panel of experts develop roadmap for preventing youth suicide (United States)

Group psychoeducation could be effective in treating patients in early stages of bipolar disorder (United Kingdom) 

Children of parents with serious mental illness: With whom do they grow up?- A prospective, population-based study (Denmark)

September 2016

WPA-funded global survey reveals level of discrimination faced by people with mental health problems (Global)

Is age of onset associated with severity, prognosis, and clinical features in bipolar disorder?: A meta-analytic review (Australia)

Study offers clues about how genetic mutations can increase risk of psychiatric disorders (Canada)

Learning to downregulate amygdala activity could help gain control of emotional responses (Israel) 

Recruitment Begins for Landmark Study of Adolescent Brain Development (United States)

Component of general anesthetic shows improvement in patients with treatment-resistant depression (United States)

August 2016

Effective self-management strategies for bipolar disorder: A community-engaged Delphi Consensus Consultation study (Canada and Australia)

Antibiotic usage, infections may contribute to manic episodes in people with mental disorders (United States)

Researchers identify reason why antidepressants take so long to work (United States) 

Simple, inexpensive psychotherapy treatment as effective as CBT for treating depression in adults (United Kingdom)

July 2016

Antibiotic usage, infections may contribute to manic episodes in people with mental disorders (United States)

Does Dialectal Behavioral Therapy (DBT) Actually Change the Way the Brain Works? (United States)

Bipolar II disorder as a risk factor for postpartum depression (Italy, Belgium, Austria, Israel, United Kingdom)

Early effects of modern electroconvulsive therapy on subjective memory in patients with mania or depression (Turkey)

Researchers link genes within striatum to bipolar disorder (United States)

Age of onset of bipolar disorder: Combined effect of childhood adversity and familial loading of psychiatric disorders. (United States, United Kingdom, The Netherlands)

Study finds link between cortisol levels and obesity in patients with bipolar disorder or recurrent depressions (Sweden)

Comorbidity of bipolar and substance use disorders in national surveys of general populations, 1990-2015: Systematic review and meta-analysis (Australia)

June 2016

Blue-blocking glasses as additive treatment for mania (Norway)

Researcher explores whether Deep Brain Stimulation can help improve life of bipolar disorder patients (United States)

Psychosocial treatment for bipolar depression: Results from STEP-BD (United States)

Actigraphic features of bipolar disorder: a systematic review and meta-analysis (Italy and United Kingdom)

May 2016

Effectiveness of cognitive behavioral therapy in treating bipolar disorder: An updated meta-analysis with randomized controlled trials (China and United States)

Safety of selective serotonin reuptake inhibitors in pregnancy: A review of current evidence (Canada and United States) 

Nutritional supplements can enhance effectiveness of antidepressants (Australia) 

April 2016

Evidence-based guidelines for treating bipolar disorder: Revised third edition recommendations from the British Association for Psychopharmacology (United Kingdom)

Scientists identify genetic variants that may influence wellbeing, depression and neuroticism (Netherlands and United States)

Ketamine for treatment-resistant unipolar and bipolar major depression: Critical review and implications for clinical practice (United States)

The relationships between depression and actual and perceived Facebook social support (Belgium and United States)

Discovery may provide potential target for new therapies to treat bipolar disorder (United States)

March 2016

Anti-inflammatory agents in the treatment of bipolar depression: A systematic review and meta-analysis (Canada, Australia, Denmark, and Brazil)

Exercise in bipolar patients: A systematic review (Brazil)

Large Study Ties Genes to Variable Lithium Response in Bipolar Disorder (United States)

Light therapy in the treatment of patients with bipolar depression: A meta-analytic study. (Taiwan)

People suffering from anxiety perceive the world differently than others (Israel)

February 2016

Compensatory neural connections stave off bipolar disorder onset (United States)

Low levels of cortisol in bipolar patients associated with depression, obesity and metabolic syndrome (Sweden)

Early intervention treatment at home, school can help young people with psychotic-like symptoms (Finland)

What happens to the course of bipolar disorder after electroconvulsive therapy? (Italy)

Rapid versus non-rapid cycling bipolar II depression: response to venlafaxine and lithium and hypomanic risk (United States)

An assessment of the anti-fatigue effects of ketamine from a double-blind, placebo-controlled, crossover study in bipolar disorder (United States)

Actigraph measures discriminate pediatric bipolar disorder from attention-deficit/hyperactivity disorder and typically developing controls (United States)

January 2016

Add-on lamotrigine enhances bipolar depression treatment (United Kingdom)

Naturally occurring changes in brain wiring can help patients avert onset of bipolar disorder (United States)

Low levels of cortisol in bipolar patients associated with depression, obesity and metabolic syndrome (Sweden)

Researchers identify inherited traits related to sleep, wake and activity cycles (United States)

December 2015

Gene variant linked to psychotic symptoms, cognitive impairment in people with bipolar disorder identified (Sweden)

Mayo Clinic investigators discover potential diagnostic markers for bipolar I disorder (United States)

Improving the Outcomes of Transition Age Youth with Psychiatric Disabilities through the Adoption and Use of Best Practice Transition Planning (United States)

Differentiation between major depressive disorder and bipolar disorder by auditory steady-state responses (Japan)

Novel antidepressant appears to be safe, effective against depression in clinical trial (United States)

UW-Madison scientist creates serotonin neurons from stem cells (United States)

November 2015

Researchers find lower levels of omega-3 fatty acids in people with bipolar disorder (United States)

Personality disorders and suicide attempts in unipolar and bipolar mood disorders (Finland)

Validity of the 6 minute walk test in outpatients with bipolar disorder (Belgium)

Brain patterns in ADHD and bipolar disorder (United Kingdom)

Quality of sleep in patients with bipolar I disorder during remission (India)

Report on Inpatients Formally Detained in Hospitals Under the Mental Health Act (United Kingdom)

October 2015

Scientists discover biological markers for bipolar disorder (Russia)

Bipolar patients' brain cells predict response to lithium (United States)

Team-based, coordinated specialty care approach produces better outcomes for people with first episode psychosis (United States)

New research may have profound impact on future development of anti-depressant medications (Israel)

Lithium can be safe, effective for children suffering from bipolar disorder (United States)

Responsiveness necessary for mental health services in Iran (Iran)

Neurocrine Biosciences announces positive data from NBI-98854 Phase III trial in tardive dyskinesia (United States)